Bottom Line for best absorption, take strontium separately from other minerals. Good morning Farah, My question: does Strontiums effect, in ranelate or citrate form, on osteoblasts and osteoclasts form the inference that fractures are reduced or has this been directly studied or proven perhaps even in the full studies which I have not read yet? You are most likely an ambassador of new information for your doctor, and hopefully, what will be learned will get passed on to help other patients as well. The best time to take fat-soluble vitamins like vitamin D, A, and K is with a meal containing fats. No worries it took me months to figure this out. PMID: 20932272, This last paper is of especial importance since it shows low intensity pulsed ultrasound therapy does not promote cancer here is a quote from the conclusion of this paper: I do not recommend taking 750 mg/d. Thus, I am unable to read the paper in which 170 mg of strontium is said to be more effective, so I do not know what was done and cannot give you more helpful feedback on this. Thats a big win when you normally would have been losing bone density! Great questions! Firstly sincere thanks and appreciation for the contents of this blog. Magnesium (as Phosphate) 21mg We already can get this information for some things for example, my genetic inheritance includes a SNP that makes my vitamin D receptors less able to latch on to vitamin D, so I need much more vitamin D than the average person to get my levels into a healthy range. I should have been Thanks, Shaine. I needs to spend some time learning more or working out more. The end result was that more calcium (Ca2+) was deposited in AlgaeCal treated cells (2.0-fold more than controls, 1.0-fold more than calcium carbonate, and 4.0-fold more than calcium citrate-treated cells). Secondly I have recently found reference to Pulsed Signal Therapy which appears to be a recent development of older techniques. My primary care physician started prescribing me the 1mg estradiol, and I also take in addition the AlgaeCal & Strontium Boost. bdcdgfeeedcg. Since your supplement is giving you 750 mg of strontium in 3 capsules, it looks like you are taking a different strontium citrate supplement. AP/SB, as the research shows (3rd study), can turn this around even in postmenopausal women losing at least 2% or more annually. I am asking because I am getting small, itchy red bumps on my skin as well as my ski feeling kind of sun burned and wondering if it could be related to the strontium citrate. Ive seen this mentioned in comments on several websites. All the ranelic acid present in strontium ranelate does not quickly disassociate from strontium in the digestive tract; some strontium ranelate is absorbed intact. So Ive got my algae cal my strontium, Im having my vitamin d levels checked and my doctor was very sympathetic to the regime I wanted to try.I took my 3 strontium tablets (strontium boost) last night and, trying to phrase this delicately, three hours later I was trotting to the loo. My kidneys are getting old. Mechanisms of action and therapeutic potential of strontium in bone. We can help guide each other towards what is highly likely to be beneficial we cannot be each other. My bones have been in excellent shape now for more than 6 years (within 6 months after I started taking AlgaeCal Plus), but I continue to take a half dose (1 capsule) of Strontium Boost daily to ensure they stay healthy! So, yes, I would take more vitamin K2. What all this means is that infection with Clostridia is not at all uncommon and in people who are infected with Clostridia, consuming citrate turns up the activity of this pathogenic bacteria, which produces and releases some really toxic stuff that can cause all the symptoms you mention. Hi Lara, But now, after my in-depth review of the current research on strontium which involved reading more than 70 recently published papers in the peer-reviewed medical literature I am convinced that strontium citrate has so much to offer that will help ensure my bones remain healthy that Ive begun supplementing with Strontium Boost again! This is the dose that has been used in almost all the human research conducted on stable strontium salts. Subjects with osteoporosis were not told to go home and do 300 jumping jacks. For your 3rd question, in Lara Pizzornos book Healthy Bones, Healthy You, she advises that In humans, strontium elimination from the skeleton occurs in 2 phases: an initial rapid clearancewhere 50% will be eliminated within 41 days followed by a slower phase of elimination during which the remaining half is lost over the following 3 years. First, does strontium expire? Thank you againAudrey. Once again I am taking 7000 D3 and am needing about another 100 mcg of MK7 (90 mcg is also OK). 2017 Feb;105(2):433-442. doi: 10.1002/jbm.a.35917. Within a year after I began supplementing with AlgaeCal Plus and Strontium Boost (680 mg strontium citrate daily), my bones were completely healthy. 5 people found this helpful. postmenopausal vertebral osteoporosisa 2-year randomized placebo controlled (I will be publishing a post on its positive bone-building mechanisms in the near future.). Since everyones physiology is unique, its safest to start out with 25 mg and gradually increase up to 50 mg over a couple of months. Radioactive strontium, which shows up in imaging and is easily traced, is often substituted for calcium in kinetic research because strontium and calcium behave very much alike in the human body. Also, Is it OK to take the strontium with a banana? I found a number of recent papers. There are only 360 mg of calcium in the two tablets listed as serving size. I was wondering if you had seen this article from Univ of Toronto, re lyme (borrelia burgdorferi) causing bone loss? I have been taking Pure Encapsulations Strontium as per doctors suggestion, but have run out of it. I like to get vegetables in as much as possible. Here is the link: http://orbi.ulg.ac.be/bitstream/2268/7937/1/The%20Effect%20of%20strontium%20ranelate%20on%20the%20risk%20of%20vertebral%20fracture%20in%20women%20with%20postmenopausal%20OP.pdf, Here is his 2002 article which is the one being cited. A more accurate answer depends on the drugs you are taking and your medical conditions. Combined with X-ray diffraction and secondary Raman spectroscopic images, it was demonstrated that strontium was dose-dependently taken up by the bone mineral and heterogeneously distributed in compact and cancellous bone, with a higher amount in newly formed bone tissue than in old bone tissue. Why is it so much more effective? However, you must take Strontium either without food or if with a meal, it should be a meal that does not contain calcium. However, strontium ranelate and radioactive (unstable) strontium are not safe due to risks and unwanted side effects. She is only 18 years of age, also it is secondary cancer not the primary. When I started him on this protocol about a year ago now, he was limping, wearing a knee brace, and fearing his bball playing days were over. Oncol Rep. 2012 Aug;28(2):481-6. doi: 10.3892/or.2012.1816. Why? (Is the sentence you quoted somewhere in the full paper? I hope you will give AlgaeCal a try when you need to reorder you calcium supps. If this does not help, you should see your doctor to rule out other causes of gastritis (stomach inflammation), such as H. pylori infection or problems with your gallbladder or pancreas both of which are involved in digestion (the gallbladder secretes bile, pancreas produces pancreatic enzymes), so their dysfunction can cause nausea. 2012 Jan;112:212-7. doi: 10.1016/j.envres.2011.11.005. Be well! Assuming that I have improved, what is the suggested dosage for each of these nutrients? Strontium and calcium share a common carrier system in the intestinal wall, which will. My hair started falling out and I read it might be the strontium so I cut back to 380 strontium. MATERIALS AND METHODS: The intestinal permeabilities of 14 drugs and three drug-like compounds with different absorption mechanisms in rat and human jejunum were determined by in situ intestinal perfusion. If you follow the dietary recommendations in Your Bones, you will lower your blood pressure along with your risks for virtually all chronic degenerative diseases, and build healthy bones along with overall good health. When it was created, its claim to fame was that it was supposed to be competely inert, and would just zip through our bodies without doing anything, and it was supposed to be completely excreted. That is troubling to me as do not want to end up with hyper-calcium. The information on Algaecal sounds good, but I would like to hear a recommendation fom someone besides the people selling the product. In the research, approximately 50% of the increase seen in BMD over 3 years of treatment with strontium was due to strontiums larger size, AND 50% of the increase seen in BMD was accurate. Re pulsed signal therapy this also looks both safe and helpful. It's not known if strontium contained in dietary supplements has these effects. (You can read about my journey from rapidly advancing osteopenia in my early 40s back to healthy bones). femoral neck] last July, I have been following the Save our Bones programme, taking Raw Calcium, a special over 50 muli- vitamin and other supplements. And, of course, you can run a search for food sources of calcium and magnesium on the internet to get this information. this does not seem like it honors the natural biological process of building bone structure. Often what is listed as a serving is less than we typically consume or far more, so do double check. A good b-complex product to take with it is B-right from Jarrow Formulas. This test was measured against a Dexa Scan from 2011 when I had also been taking strontium citrate. I suggest the following: Print your own How to Take Your AlgaeCal Supplements PDF. I have a question please. Will the trace minerals in AlgaeCal be enough on a daily basis or do I need to supplement? The ability of this IVXRF system to monitor and measure bone strontium levels over time provides a useful diagnostic tool to help gain insight into strontium bone kinetics. If you do have a choice, PLEASE use the natural form of strontium. Hi Tyler, PMID: 20965537, Ferreri SL, Talish R, Trandafir T, Qin YX. The two-capsule dose of strontium citrate = 680 mg, which provides 236 mg of elemental strontium + 440 mg of citrate.. You can wear a hat and put sunscreen on your face to prevent wrinkling and age spots, but leave at least your arms and legs bare and sunbathe. But I really struggled with smell and the slimy coating. A randomized, multicenter, double-blind, placebo-controlled trial was undertaken in 353 osteoporotic women with at least one previous vertebral fracture and a lumbar T-score <-2.4. Reading your book and following all your posts has really helped me. Personally, I rely upon both vitamin A, which I take in an amount equivalent to the vitamin D3 I need to take, and 2 tablespoons of Triple Power each day, to keep my inflammation down and to protect not just my bones but my overall health. You do NOT want to take 10 milligrams of MK-7 daily! God Bless, Marilyn. Please feel free to contact our Bone Health Consultants 7 days a week at 1-800-820-0184 (USA & Canada, toll-free) or email [emailprotected] for more information and personalized support! three meals of the day, equally effective. Various anti-osteoporotic agents are available for clinical use; however, there is still a need for drugs able to positively influence the coupling between bone formation and bone resorption to increase bone mass and bone strength. We would love to work with you further to determine whats causing this and help find a solution. PubMed, Web of Science, Scopus, HighWire and Google scholar) for all the articles by Meunier and found over 150 articles relating to strontium in which he was involved. In the U.S., Your Bones was approved by our library book review system and is available in our public libraries as well. http://www.bodybuilding.com/store/jarrow/bright.html Obviously, what you are currently doing is not meeting YOUR needs. Farah, Hi Farah, It's not known if strontium. Cannata, J., Balogh, A., Lemmel, E. M., Pors-Nielsen, S., Rizzoli, R., Genant, H. You can further optimize your absorption of strontium by: Ensuring your intake of vitamin D3 is adequate. That's because your body only takes in what it needs and the rest is excreted through urine. Lastly, and to me the most important point, is that strontium does not improve bone health, resistance to fracture, by increasing BMD. (Moise H, Adachi JD, Chettle DR, et al. Strontium is a very helpful mineral it lessens osteoclast activity AND boosts osteoblast activity, so I will continue to take some even after I am no longer even osteopenic, which I expect to happen within a year or two at most. One capsule gives us 118 mg of strontium and 220 mg of citrate. Calcium is best absorbed when it's taken in smaller doses (typically less than 600 milligrams at one time). I am on your bone building plan from your book and taking Algae Cal and Strontium. If you dont have a copy, please check it out from your library if you dont wish to buy it. Cortical bone also accumulates far more slowly. Bone. I have a green smoothie at least 5 days a week with collards or kale. Although my bones have now been in excellent shape for several years (I was still osteopenic when I began taking AlgaeCal Plus & Strontium Boost, which fully restored the health of my bones after just 6 months), I continue to take Strontium Boost as well as AlgaeCal Plus to ensure my bones remain strong and healthy. I cannot emphasize this enough. Although many people have never heard of it before, it's a very interesting and somewhat controversial supplement. Re: Life Extension K2 There are two available K2 products from them. Could the Strontium be causing it and should I reduce the dose? Aside from it, I was diagnosed with a bit high cholesterol level and a bit high of creatinine and on medication for this in one month. I explain all this in detail in Your Bones, 2nd edition, pp. Over-expression of the ERBB2 gene (also referred to as amplification), occurs in approximately 15-30% of breast cancers and has been shown to play a role in the development and progression of certain types (the ER+ or HER2/Neu+) breast cancers. Ranelic acid is a new to nature compound, synthesized in a lab by a pharmaceutical company so they could combine it with strontium and thus patent the result the purpose of this is to make money, no other reason. Another fact: strontium is the only trace mineral present in human bone whose level in bone correlates with bone compressive strength, i.e., resistance to fracture. Do you agree, disagree? A comparison of adverse event and fracture efficacy data for strontium ranelate in regulatory documents and the publication record. Epub 2010 Mar 16. Review. 2) Delannoy P, Bazot D, Marie PJ. This is what I do for myself. Mineral substance is crystallized as nonstoichiometric carbonated apatite ionic crystals of small size and extended specific surface. Also, you need to check to see if the drug(s) you are taking interact adversely. She may know of me, but will certainly know of my husband, Dr. Joe Pizzornohe has been on the IFM board for 20+ years, is one of their Linus Pauling Award recipients, and served as Chair of the IFM Board for a number of years. I will be 69 this year, and took my share of the old kind of Estrogen. I am wondering what to do? I want to underscore here that this is a competition that calcium always wins, which explains why: Ok, now that you see the differences in the 3 main types of strontium, lets dig into the common misconceptions surrounding this valuable mineral. Heres a link to my talk on TBS: https://blog.algaecal.com/how-to-analyze-your-dexa-results-for-bone-quality/ The really good news is that your DXA images can be used to calculate your TBS, so please request that this be done for you when you go in for your next DXA. DXA only checks BMD, which is a measure of quantity. I, personally, use AlgaeCals strontium supplement; I know AlgaeCal has the highest standards for its supplements purity and potency, but other companies here also offer strontium citrate. PMID: 841579. BE WELL! Safety does come first for me, and if at 41 mg/day they saw changes in thyroid I would like to take less. am presently in my third year taking it. Im barely osteopenic now, but continue to take 340 mg of strontium most days (I sometimes forget as I take mine with lunch, or I realize that I just ate a cup of yogurt so the calcium, which competes with strontium for absorption and will always win out over strontium, most likely blocked much benefit from the strontium that day). PLEASE read up! Excellent material. Luckily, strontium has science to back it up and someone (i.e. The reason for this is that strontium is very slow to be absorbed by the body. In most people, strontiums effects on glutamate secretion promote relaxation and deeper, more restful sleep, but in some people, these effects cause next day grogginess or nap attacks. You could try taking your Strontium mid-day to see if this helps. These techniques were applied on bone mineral samples obtained from the iliac crest of male cynomolgus monkeys treated for 13 weeks with oral doses of strontium ranelate. If you have low bone density, you will receive the most benefit from a 680 milligram per day dose of strontium citrate. Once bone health is restored, a maintenance dose of 340 mg per day should be both safe and sufficient. Secondly, Strontium Boost is strontium citrate. If so, then I think your plan is excellent. I am NOT paid by AlgaeCal to promote its products. Calcium and magnesium balance one another in many, many activities in our bodies. Hi Tyler, If you want to read more about all this, the head of the research team primarily involved (now at Harvard) is Alessio Fassano, MD. Do you have any recommendations before getting the scan as far as discontinuing either the algae cal or strontium or any other minerals or vitamins? Watch acid/alkali balance. sml, Hi sml, Heres the math on this: 1.04% x .915 (100%-8.5% = 91.5) = an increase in BMD of 0.95. A number of medical experts now recommend that, once bone density has moved out of osteoporotic and into osteopenic range (which you now are), the dose of strontium citrate can be cut in half. If I end up having dairy foods (like cottage cheese or yogurt or cheese) at lunch, I just take the strontium around 4 pm with a dairy free snack. I read the article by Meunier that he cited, but it was evident that said article supported 680 mg not 170 mg to be the most effective. Interesting article. I did return your call did you get the message I left for you? Hi Lara Both minerals share a common carrier system in the intestinal wall, which will always choose to transport calcium rather than strontium from our digestive tract into our bloodstream. If so, have you had your blood levels of 25(OH)D checked? can I take just the AlgaeCal without Strontium? Kroes, R., et al. We dont recommend taking another calcium supplement with AlgaeCal. I love to exercise, have been addicted to barre classes for the last year and a half, and push my body quite hard, taking one class every day and two back-to-back classes on the weekends. MK-4 was the preferred way to go on NOF before you started posting. I will look into the Algaecal when my stock of Ca/Mg supps gets down to reorder level. Any ideas as to why I could be high here? Lara: The incorporation of strontium into bone after oral strontium treatment depends upon the skeletal site more specifically, the amount of trabecular vs cortical bone in the skeletal site. Hi Barbara delighted you are getting well informed and taking the best care of your bones (and all the rest of you if you are eating the healthy diet and following the exercise recommendations in Your Bones). It took several years for my hair to fill back in. From Laras Comment at bottom of: Strontium Side Effects are Overblown Get the Facts: Strontium is almost twice as large as calcium, and its larger size does affect DXA readings. I found NOF, and actually they did a good job of alarming me. If you do decide to reintroduce it, we would suggest trying a half dose (1 capsule) to start. Vitamin A. Vitamin D. Vitamin E. Vitamin K. For maximum absorption, the best time to take vitamin D and other fat-soluble vitamins is after you've eaten foods that contain fat. You can, however, run another type of test that will show you whether you are continuing to lose bone every month until your results show you are no longer losing bone and are stable. Depending on the amount of food consumed, the sensation may take hours to return. BMC Musculoskelet Disord. I backed off and started with just Algae Cal 2 capsules at breakfast and things went back to normal. However and this is why I am unable to tell you exactly how much strontium is deposited in cortical and in trabecular bone in real individual people the strontium signal varied widely between individuals such that after three years, the highest strontium signal observed was 28.15 for the finger (cortical bone) and 26.47 for the ankle in one volunteer and only 3.15 for the finger (cortical) and 4.46 for the ankle (trabecular) bone in another. I discuss this on the AlgaeCal Community in an #AskLara on testing that identifies C.diff and other pathogens. There are quite a few other delicious grains we can have including quinoa, millet, brown rice if we want the extra carbs. Glucocorticoid-induced osteoporosis.Clin Exp Rheumatol. Because PTH exhibits an exaggerated response to any calcium, it is not considered a valid measurement by researchers in bone health. From 2011 when i had also been taking Pure Encapsulations strontium as per doctors suggestion but... 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